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The peptide has also demonstrated interactions with the dopaminergic and serotonergic systems, with studies showing that BPC-157 can modulate the effects of dopamine-related agents in animal models and counteract some behavioural and neurochemical consequences of both dopamine agonists and antagonists (Sikiric et al., 2010)

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6 Enzyme & NAD+ Shifts: Reduced NNMT activity and increased nicotinamide availability, which might support the NAD+ salvage pathway